"What's your favorite scary movie?"
Ghostface is an identity taken on by multiple people. The persona was created by Billy Loomis and Stu Macher. The overall physical persona of Ghostface consists of a dime-a-dozen Halloween costume labeled Father Death and a voice changer.
- Billy Loomis: Sidney Prescott's ex-boyfriend. A charismatic psychopath obsessed with horror movies. Along with Stu Macher, Billy killed Maureen Prescott as revenge for sleeping with his father and breaking apart his family. A year later, he became Ghostface along with Stu to kill their friends and make themselves famous by being survivors.
- Stu Macher: A psychotic and morbid teen also obsessed with horror movies. Stu became Ghostface with Billy to get back at his ex-girlfriend and her new boyfriend.
- Debbie Loomis: The mother of Billy Loomis. She became Ghostface along with Mickey, to kill Sidney as revenge for killing her son.
- Mickey Altieri: A friend of Sidney's, the accomplice of Debbie Loomis, and a sociopath. Debbie found him on the internet and used him for her plan. Mickey wanted to get caught and blame the killings on horror movies.
- Roman Bridger: A famous director, Sidney's half-brother, and the mastermind behind the Woodsboro Massacre. Roman showed Billy a recording of his father going to meet Maureen in a motel, and convinced him to commit the murders with Stu. He became Ghostface to torment and frame his half-sister for having the love of his mother.
- Jill Roberts: The cousin of Sidney Prescott. Jill became Ghostface in order to become famous by being the sole survivor of the murders.
- Charlie Walker: A movie and tech geek and accomplice of Jill Roberts. Charlie was convinced by Jill into becoming Ghostface with her.